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Posts Tagged ‘Research’

SmartSensors

The emergence of new production philosophies, initiated by the FDA’s PAT initiative and in particular the German government’s future project Industry 4.0, has led to a reorientation of sensor technology, which will be trend-setting for biotechnology processes with their special requirements – especially continuous and/or integrated production – in the coming years. Under the maxim of process observability and controllability,a clear trend towards smart sensors with a clear focus on sensor intelligence, decentralization, multi-sensor systems and miniaturization has become apparent.

How to avoid drowning in the data flood

Driven by the state initiative of the future project Industry 4.0, the real and virtual world merge into the Internet of Things. Through intelligent methods of process monitoring and decision making, production processes, companies and complete value chains are to be controlled and optimized almost in real time. In the context of a holistic and sustainable implementation of the vision of the intelligent company, it is particularly important for the field of biotechnology with its high demands on product quality and safety as well as the sometimes highly complex production processes and structures to obtain reliable data for production control. More and more modular, intelligent and networked components must make this data available and via integrated analytical tools take over the simult

aneous evaluation of this flood of data. In this context, smart sensors are sensors that perform complex signal processing tasks in addition to the actual measurement task, can be parameterized and diagnosed and can provide additional information about themselves and the process environment.

Especially for the applicability to biotechnological processes, the following elements of extended sensor intelligence are of essential importance, as they will provide users with greater process reliability as well as cost and time savings:

  • Self-diagnosis, self-identification and reporting of one’s own status
  • Possibility of executing decentralised logic functions (If-Then) and processing complete process functions (only result is reported to PLC) for increasing process reliability and reducing the volume of data to be transmitted
  • Independent validity check of the measured values and adequate information summary
  • Selection and evaluation of process profiles, characteristics and parameters and transfer to status and status messages such as „in control“ or „out of control”
  • direct interaction with assigned actors via decentralised control units
  • Trend determination and prediction of process flows

The extension of sensor intelligence is particularly important for its applicability to biotechnological processes. The possibility of self-diagnosis, self-identification and reporting of the own status should take place in the sensor, so that an independent validity check of the measured values can be transferred to the control system. As a result, the routine testing work in the laboratory can be reduced. Checks are only carried out when necessary and the personnel capacities released as a result can be re-allocated in the company to add value.

Requirements for sensors in biotechnology

The prerequisite for this is an adequate information summary of the available data and suitable data preprocessing with the execution of decentralized logic functions. In this way, the smart sensor can independently record process events and evaluate the determined events using a corresponding functionality (e.g. correlation analyses of abiotic and biotic data).  The actual control is transferred for further processing in the control cycle. The independent process analysis, parameter evaluation and decision making of the individual sensor or in combination, for example as a multi-agent framework, offers enormous potential in terms of optimising and increasing the efficiency of bioprocesses. In particular, the complex topic of population heterogeneity and the use of complex substrate matrices open up a broad spectrum to explore the possibilities and limitations of the smart sensors with regard to innovative population concepts and models.

This text is an excerpt of the position paper “Smarte Sensoren für die Biotechnologie”, DECHEMA 2017. If you want to learn more about the concept, applications and technologies for smart sensors, join the conference „Smart Sensors – mechanistic and data driven modelling“ on 1-2 October 2018, Frankfurt.

 

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Update | April 2018
Dear reader,

Through this BioLinX Update we offer those who are not aware yet, the opportunity to still participate in one of our 4 upcoming events. These events are either hosted by BioLinX, or we partner up in organizing them. Join in now! Through, among other things, these events BioLinX has already contributed to the success of well over 500 unique projects and/or companies. 

UPCOMING EVENTS

10-11 April | Finance Academy | Milan, Italy

The 3rd edition of our succesful ‘Finance Academy & Brokerage’ format. After the Netherlands and Sweden, this event now visits Milan. What to expect:

On April 10th , companies attend our free coaching session on ‘VC-pitching’. Experienced coaches from relevant industry areas  prepare presenters for their participation in the Finance Academy the following day.

April 11th, participants present their business projects and network to the audience of experts in innovation, Business Angels, Venture Capitalists, Corporate and Institutional investors and peers and are reviewed by the Expert Jury. Still a few seats left, but please note: registration for the Finance Academy closes on April 6th!!

11 April | Brokerage Event in connection with Finance Academy | Milan, Italy

Federchimica – the Italian Federation of Chemical Industries  and its relevant sectoral associations host BioLinX’s Brokerage event focusing on promising bioeconomy value chains and innovative initiatives exploiting industrial biotechnologies, bio-sourcing raw materials and/or bio-transforming products. Focus on value chains such as cosmetics, detergents and cleaning products, industrial biotech and foodingredients.

For programme and registration: http://www.biolinx-project.eu/event/circular-bioeconomy-workshop-italy

12 April | Webinar on EU’s LIFE Programme| online

BioLInX’ experts inform you on if and how your biobased and environmental-friendly technology, process or product can benefit from EU’s LIFE funding programme. In recent years, the programme has supported a variety of bio-based projects with a funding of up to 60%.

Thursday 12 April 2018, 10:30 – 11:30 hrs CET

During this webinar you will learn more about
·         the LIFE programme
·         the main criteria
·         eligible activities
·         the preparation of a 10-page concept note for the upcoming deadline on 12 June 2018. 

Registration is free of charge. You can register here: http://online.cme24.de/index.php?id=1076

25-26 April | Online Matchmaking

BioLinX Online Brokerage is an innovation exchange and a matchmaking platform serving SMEs, academia and large companies. If you are looking for new business partners, exciting inventions, new products and services or investments, BioLinX will connect you with right people from the European bio-economy community.

Why should you participate? You will save time and costs, avoid unnecessary business trips, meet  experts from all over Europe and make it quick and easy to pinpoint offers and requests.

Register for participation on biolinx.talkb2b.net/members/register

16 May | Pitching & Networking Event| Bratislava, Slovakia

Wondering what the umbrella term bioeconomy means and how it might be  relevant to you? Interested in how innovative ideas in the agrifood sector can take off, reach scale and receive EU funding? Join us at ther pitching and networking event in Bratislava on the 16th May 2018, and find out more about it with leading technology and funding experts.

During the event, you can pitch your company and expertise to bio-experts and benefit from the networking opportunity. The participant delivering the best pitch (chosen by a jury of bio experts) will receive a free EU grant scan service from BioLinX partner, PNO Consultants.

We look forward to meeting you during one of these four events!

 BioLinX?

Would you like more details on what we have to offer and to whom in particular we offer it?

Read our brochure or visit our website!

Kind regards on behalf of the BioLinX Consortium,

Dennis van der Pas (coordinator BioLinX)
d.vanderpas@rewin.nl

 

BioLinX Project provides links to commercialize your innovative idea

www.BioLinX-project.eu

     @BioLinXproject

BioLinX is a H2020 project, with the goal to support H2020 and FP7 projects in commercializing their innovative ideas and to connect them to new regional networks and markets. This project has received funding from the European Union’s Horizon 2020 research and innovationprogramme under grant agreement No 65269.                                                                                                         

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